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Article

The promoter region of the CTLA4 gene is associated with type 1 diabetes mellitus.

Journal of pediatric endocrinology & metabolism : JPEM - 1 Apr 2001

Lee Y J, Lo F S, Shu S G, Wang C H, Huang C Y, Liu H F, Wu C C, Yang T Y, Chang J G

Abstract excerpt

The CTLA4 (cytotoxic T lymphocyte associated antigen-4) gene encodes the T cell receptor involved in the control of T cell proliferation and mediates T cell apoptosis. C-T polymorphism is present at position -318 from the ATG start codon in the promoter region of the gene. We report a study on the polymorphism in 347 unrelated children with type 1 diabetes mellitus (DM) (age at diagnosis 7.2+/-3.8 years) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 11327371
DOI: 10.1515/jpem.2001.14.4.383

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The promoter region of the CTLA4 gene is associated with type 1 diabetes mellitus.PMID 11327371Read ↗

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