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Article

A major susceptibility locus on chromosome 22q12 plays a critical role in the control of kala-azar.

American journal of human genetics - 1 Nov 2003

Bucheton Bruno, Abel Laurent, El-Safi Sayda, Kheir Musa M, Pavek Sylvana, Lemainque Arnaud, Dessein Alain J

Abstract excerpt

Kala-azar (KA) is a life-threatening protozoal disease caused by Leishmania parasites (L. donovani, L. chagasi, and L. infantum). The disease, which is also called "visceral leishmaniasis," is prevalent in Africa, South America, Asia, and the Mediterranean basin. Epidemics occur periodically, killing a large number of infected individuals. Factors determining whether a patient remains asymptomatic or develops KA...

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Identifiers

PMID: 14557985
DOI: 10.1086/379084
PMCID: PMC1180485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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