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Article

Y chromosome lineage- and village-specific genes on chromosomes 1p22 and 6q27 control visceral leishmaniasis in Sudan.

PLoS genetics - 11 May 2007

Miller E Nancy, Fadl Manal, Mohamed Hiba S, Elzein Abier, Jamieson Sarra E, Cordell Heather J, Peacock Christopher S, Fakiola Michaela, Raju Madhuri, Khalil Eltahir A, Elhassan Ahmed, Musa Ahmed M, Ibrahim Muntaser E, Blackwell Jenefer M

Abstract excerpt

Familial clustering and ethnic differences suggest that visceral leishmaniasis caused by Leishmania donovani is under genetic control. A recent genome scan provided evidence for a major susceptibility gene on Chromosome 22q12 in the Aringa ethnic group in Sudan. We now report a genome-wide scan using 69 families with 173 affected relatives from two villages occupied by the related Masalit ethnic group. A primary...

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PMID: 17500593
DOI: 10.1371/journal.pgen.0030071
PMCID: PMC1866354

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Source receipt: pubmed, retrieved 6 Sept 2026.

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