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Article

G protein beta 3 subunit 825T allele carriage and risk of coronary artery disease.

Atherosclerosis - 1 Mar 2003

von Beckerath Nicolas, Schusterschitz Yasmin, Koch Werner, Griesser Korinna, Mehilli Julinda, Gorchakova Olga, Schömig Albert, Kastrati Adnan

Abstract excerpt

C825T polymorphism in the G protein beta3 subunit gene (GNB3) is associated with increased transmembrane signal transduction via adenylyl cyclase inhibiting G (G(i)) proteins. We tested whether GNB3 C825T is associated with an increased risk of coronary artery disease (CAD). Genotypes were determined with polymerase chain reaction and allele-specific fluorogenic probes. Angiographically examined, consecutive...

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Source

Identifiers

PMID: 12618278
DOI: 10.1016/s0021-9150(02)00422-7

Genes

CAD
GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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