Article
GNB3 c.825C>T (rs5443) Polymorphism and Risk of Acute Cardiovascular Events after Renal Allograft Transplant
International journal of molecular sciences - 29 Aug 2022
Peitz Tobias, Möhlendick Birte, Siffert Winfried, Heinemann Falko Markus, Kribben Andreas, Eisenberger Ute, Friebus-Kardash Justa
Abstract excerpt
The c.825C>T single-nucleotide polymorphism (rs5443) of the guanine nucleotide-binding protein subunit β3 (GNB3) results in increased intracellular signal transduction via G-proteins. The present study investigated the effect of the GNB3 c.825C>T polymorphism on cardiovascular events among renal allograft recipients posttransplant. Our retrospective study involved 436 renal allograft recipients who were followed...
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