Article
G-protein beta3 subunit (GNB3) gene polymorphisms and cardiovascular disease: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study.
Atherosclerosis - 1 May 2007
Renner Wilfried, Hoffmann Michael M, Grünbacher Gerda, Winkelmann Bernhard R, Boehm Bernhard O, März Winfried
Abstract excerpt
A common 825C>T polymorphism in exon 10 of the gene for the beta-3 subunit of heterotrimeric G-proteins, GNB3, has been associated in some studies with traits of the metabolic syndrome as well as coronary artery disease (CAD), but these associations were refuted by other studies. To investigate the role of GNB3 gene variations in CAD and myocardial infarction (MI), we determined five GNB3 polymorphisms (-1429G>A,...
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