Article
[Association of GNB3 gene C825T polymorphism with coronary heart disease].
Genetika - 1 Aug 2007
Nikitin A G, Chudakova D A, Spitsina E V, Minushkina L O, Zateĭshchikov D A, Nosikov V V, Debabov V G
Abstract excerpt
The C825T polymorphism in the gene encoding the G protein beta 3 subunit (GNB3) causes enhanced G protein activation and the increased in vitro cell proliferation. We investigated the association of gene GNB3 C825T polymorphism with coronary artery disease (CAD) in the Russian population. A total of 313 patients with CAD diagnosed on the basis of clinical studies and coronary angyography were examined. The...
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