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Article

Intersection of the Kap123p-mediated nuclear import and ribosome export pathways.

Molecular and cellular biology - 1 Mar 2003

Sydorskyy Y, Dilworth D J, Yi E C, Goodlett D R, Wozniak R W, Aitchison J D

Abstract excerpt

Kap123p is a yeast beta-karyopherin that imports ribosomal proteins into the nucleus prior to their assembly into preribosomal particles. Surprisingly, Kap123p is not essential for growth, under normal conditions. To further explore the role of Kap123p in nucleocytoplasmic transport and ribosome biogenesis, we performed a synthetic fitness screen designed to identify genes that interact with KAP123. Through this...

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Identifiers

PMID: 12612077
DOI: 10.1128/MCB.23.6.2042-2054.2003
PMCID: PMC149464

Genes

RAI1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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