Article
Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast.
Molecular and cellular biology - 1 Apr 2002
Leslie Deena M, Grill Brock, Rout Michael P, Wozniak Richard W, Aitchison John D
Abstract excerpt
To further our understanding of how the nucleocytoplasmic transport machinery interfaces with its cargoes and how this affects cellular physiology, we investigated the molecular mechanisms of phenotypes associated with mutations in karyopherin Kap121p. Two previously unreported phenotypes of kap121 cells were observed: defects in mating and in the transition from the normal yeast form to the pseudohyphal,...
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