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Article

Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits.

The Journal of biological chemistry - 31 Dec 2004

Galani Kyriaki, Nissan T Amar, Petfalski Elisabeth, Tollervey David, Hurt Ed

Abstract excerpt

Rea1, the largest predicted protein in the yeast genome, is a member of the AAA(+) family of ATPases and is associated with pre-60 S ribosomes. Here we report that Rea1 is required for maturation and nuclear export of the pre-60 S subunit. Rea1 exhibits a predominantly nucleoplasmic localization and is present in a late pre-60 S particle together with members of the Rix1 complex. To study the role of Rea1 in...

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PMID: 15528184
DOI: 10.1074/jbc.M406876200

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GAL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rea1, a dynein-related nuclear AAA-ATPase, is involved in late rRNA processing and nuclear export of 60 S subunits.PMID 15528184Read ↗

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Rei1 and Reh1 facilitate the loading of eL24Semantic proximity Read ↗

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Surveillance of nuclear-restricted pre-ribosomes within a subnucleolar region of Saccharomyces cerevisiae.Semantic proximity Read ↗

Rrs1p, a ribosomal protein L11-binding protein, is required for nuclear export of the 60S pre-ribosomal subunit in Saccharomyces cerevisiae.Semantic proximity Read ↗

Intersection of the Kap123p-mediated nuclear import and ribosome export pathways.Semantic proximity Read ↗

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The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes.Semantic proximity Read ↗

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Rlp7p is associated with 60S preribosomes, restricted to the granular component of the nucleolus, and required for pre-rRNA processing.Semantic proximity Read ↗

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