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Article

Genetic analysis of the ribosome biogenesis factor Ltv1 of Saccharomyces cerevisiae.

Genetics - 1 Nov 2014

Merwin Jason R, Bogar Lucien B, Poggi Sarah B, Fitch Rebecca M, Johnson Arlen W, Lycan Deborah E

Abstract excerpt

Ribosome biogenesis has been studied extensively in the yeast Saccharomyces cerevisiae. Yeast Ltv1 is a conserved 40S-associated biogenesis factor that has been proposed to function in small subunit nuclear export. Here we show that Ltv1 has a canonical leucine-rich nuclear export signal (NES) at its extreme C terminus that is both necessary for Crm1 interaction and Ltv1 export. The C terminus of Ltv1 can...

Topics

Active Transport, Cell Nucleus
Amino Acid Sequence
Binding Sites
Cell Nucleus
Consensus Sequence
Genes, Dominant
Genetic Complementation Test
Green Fluorescent Proteins
Immunoprecipitation
Karyopherins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Nuclear Export Signals

Phenotype

Protein Binding

Receptors, Cytoplasmic and Nuclear

Recombinant Fusion Proteins

Ribosomal Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25213169
DOI: 10.1534/genetics.114.168294
PMCID: PMC4224153

Genes

NES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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