Article
Technique for obtaining highly enriched, quiescent immature Langerhans cells suitable for ex vivo assays.
Immunology letters - 3 Mar 2003
Tchou Isabelle, Sabido Odile, Lambert Claude, Misery Laurent, Garraud Olivier, Genin Christian
Abstract excerpt
Epidermis and surface epithelium-dendritic cells comprise of immature cells termed Langerhans cells (LCs), which express characteristically the Birbeck granules, along with surface markers such as CD1a. These cells can capture a pathogen and then migrate and differentiate to a more mature stage. During this maturation process, dentritic cells express surface markers differentially. In physio-pathological models...
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