GM-CSF promotes differentiation of a precursor cell of monocytes and Langerhans-type dendritic cells from CD34+ haemopoietic progenitor cells.

doi:10.1046/j.1365-2141.1998.00685.x

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Article

GM-CSF promotes differentiation of a precursor cell of monocytes and Langerhans-type dendritic cells from CD34+ haemopoietic progenitor cells.

British journal of haematology - 1 May 1998

Herbst B, Köhler G, Mackensen A, Veelken H, Lindemann A

Abstract excerpt

Epithelia-associated dendritic cells (DC) including Langerhans cells in the skin (LC) are precursors of lymph node located interdigitating DC (iDC). CD1a+ LC are known to be derived from CD34+ haemopoietic progenitor cells (HPC); however, cells of an intermediate differentiation state that are CD...

Topics

Antigens, CD34
Cell Differentiation
Cells, Cultured
Flow Cytometry
Granulocyte-Macrophage Colony-Stimulating Factor
Hematopoietic Stem Cells
Humans
Langerhans Cells
Microscopy, Electron
Monocytes
Phenotype

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Identifiers

PMID: 9609515
DOI: 10.1046/j.1365-2141.1998.00685.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9609515-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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