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Article

Altered short-term hippocampal synaptic plasticity in mutant alpha-synuclein transgenic mice.

Neuroreport - 10 Feb 2003

Steidl Jill V, Gomez-Isla Teresa, Mariash Ami, Ashe Karen Hsiao, Boland Linda M

Abstract excerpt

Hippocampal synaptic plasticity was studied in transgenic mice over-expressing human alpha-synuclein containing the A30P Parkinson's disease mutation. Medial perforant path-dentate granule cell synapses showed enhanced paired-pulse depression (PPD) for short interpulse intervals (< 200 ms), without differences in basal transmission. Extracellular calcium reduction failed to rescue the enhanced PPD. Paired-pulse...

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Identifiers

PMID: 12598733
DOI: 10.1097/00001756-200302100-00012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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