Article
Identification of the SRC pyrimidine-binding protein (SPy) as hnRNP K: implications in the regulation of SRC1A transcription.
Nucleic acids research - 1 Mar 2003
Ritchie Shawn A, Pasha Mohammed K, Batten Danielle J P, Sharma Rajendra K, Olson Douglas J H, Ross Andrew R S, Bonham Keith
Abstract excerpt
The human SRC gene encodes pp60(c-src), a non-receptor tyrosine kinase involved in numerous signaling pathways. Activation or overexpression of c-Src has also been linked to a number of important human cancers. Transcription of the SRC gene is complex and regulated by two closely linked but highly dissimilar promoters, each associated with its own distinct non-coding exon. In many tissues SRC expression is...
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