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Article

c-src structure in human cancers with elevated pp60c-src activity.

British journal of cancer - 1 Sept 1991

Wang P, Fromowitz F, Koslow M, Hagag N, Johnson B, Viola M

Abstract excerpt

We used RNAase protection and restriction fragment length polymorphism assays to detect activating mutations of c-src in a spectrum of human tumours. No mutations were detected at codons 98, 381, 444, and 530. We conclude that mutational activation is not the mechanism of enhancement of pp60c-src-specific kinase activity found in a number of human cancer types.

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Identifiers

PMID: 1716952
DOI: 10.1038/bjc.1991.344
PMCID: PMC1977675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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