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Article

<i>SRC</i> gene expression in human cancer: the role of transcriptional activation

1 Apr 2004

Abstract excerpt

Human pp60c-Src (or c-Src) is a 60 kDa nonreceptor tyrosine kinase encoded by the SRC gene and is the cellular homologue to the potent transforming v-Src viral oncogene. c-Src functions at the hub of a vast array of signal transduction cascades that influence cellular proliferation, differentiation, motility, and survival. c-Src activation has been documented in upwards of 50% of tumors derived from the colon,...

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Identifiers

PMID: 15060621
DOI: 10.1139/o03-077

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Source receipt: pubmed, retrieved 7 Sept 2026.

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