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Article

The Escherichia coli methyl-directed mismatch repair system repairs base pairs containing oxidative lesions.

Journal of bacteriology - 1 Mar 2003

Wyrzykowski Jennifer, Volkert Michael R

Abstract excerpt

A major role of the methyl-directed mismatch repair (MMR) system of Escherichia coli is to repair postreplicative errors. In this report, we provide evidence that MMR also acts on oxidized DNA, preventing mutagenesis. When cells deficient in MMR are grown anaerobically, spontaneous mutation frequencies are reduced compared with those of the same cells grown aerobically. In addition, we show that a dam mutant has...

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Identifiers

PMID: 12591888
DOI: 10.1128/JB.185.5.1701-1704.2003
PMCID: PMC148063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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