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Article

Replication-associated repair of adenine:8-oxoguanine mispairs by MYH.

Current biology : CB - 19 Feb 2002

Hayashi Harutoshi, Tominaga Yohei, Hirano Seiki, McKenna Allison E, Nakabeppu Yusaku, Matsumoto Yoshihiro

Abstract excerpt

Cellular DNA is constantly exposed to the risk of oxidation. 8-oxoguanine (8-oxoG) is one of the major DNA lesions generated by oxidation, which is primarily corrected by base excision repair. When it is not repaired prior to replication, replicative DNA polymerases yield misinsertion of an adenine (A) opposite the 8-oxoG on the template strand, generating an A:8-oxoG mispair. MYH, a mammalian homolog of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11864576
DOI: 10.1016/s0960-9822(02)00686-3

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PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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