Article
Atopic asthma and TNF-308 alleles: linkage disequilibrium and association analyses.
Human immunology - 1 Mar 2003
Di Somma Carmela, Charron Dominique, Deichmann Klaus, Buono Catello, Ruffilli Anna
Abstract excerpt
The association of a tumor necrosis factor -308 allele (TNF2) to asthma has been reported in some studies but not in others. The aim of this study was to test this association in a population recruited on the basis of allergy to Parietaria. In the study population, asthma was positively associated to HLA-DRB1*03 (p = 0.01) and to the haplotype TNF2/DRB1*03 (p = 0.02). In the parent subgroup, the proportion of...
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