Article
HLA-DRB1* and allergy to Parietaria: linkage and association analyses.
Human immunology - 1 Dec 1999
D'Amato M, Picardi A, Menna T, Di Somma C, Ariano R, di Pietro A, Charron D, Maggi E, Matricardi P, Plebani A, Poto S, Testa G, Sacerdoti G, Ruffilli A
Abstract excerpt
In this study, we used the affected sibling-pairs approach to investigate the linkage of HLA (human leukocyte antigen)-DRB* with phenotypes related to allergy to Parietaria, the most common pollinosis in Mediterranean countries. The study population consisted of 51 nuclear families (235 subjects). Linkage was detected with Parietaria skin test positivity (p < (0.01), presence of IgG and IgE antibodies specific...
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