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Article

An association between asthma and TNF-308G/A polymorphism: meta-analysis.

Journal of human genetics - 1 Jan 2006

Aoki Takeshi, Hirota Tomomitsu, Tamari Mayumi, Ichikawa Kunio, Takeda Kazunori, Arinami Tadao, Shibasaki Masanao, Noguchi Emiko

Abstract excerpt

Tumor necrosis factor (TNF) is a potent inflammatory cytokine that contributes to airway inflammation in asthma. Previous studies have reported that a G-to-A transition at position -308 (-308G/A, also referred to as TNF-alpha-308*1 and 308*2 respectively), is associated with asthma, but other studies have shown conflicting results. To investigate a possible association between the TNF-308G/A polymorphism and...

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Identifiers

PMID: 16865291
DOI: 10.1007/s10038-006-0007-3

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TNF

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