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HLA Dr‐Dq haplotypes and the TNFA‐308 polymorphism: associations with asthma and allergy

4 Aug 2007

Abstract excerpt

BACKGROUND: The HLA (human leukocyte antigen) class II genes DQB1 and DRB1 and the Tumor Necrosis Factor alpha gene (TNFA) within the HLA complex (chromosome 6p21) have been associated with asthma and allergy. Due to the strong linkage disequilibrium characterizing this complex and the multiple asthma/allergy expressions, we aimed to determine which of these genes were primarily involved in specific...

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PMID: 17686102
DOI: 10.1111/j.1398-9995.2007.01377.x

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