Article
Relation between tumour necrosis factor polymorphism TNFalpha-308 and risk of asthma.
European journal of human genetics : EJHG - 1 Jan 2002
Witte John S, Palmer Lyle J, O'Connor Richard D, Hopkins Penelope J, Hall Jeff M
Abstract excerpt
Tumour necrosis factor (TNF) alpha affects immune response and airway inflammation, which are characteristics of asthma. Genetic factors may impact TNFalpha levels, and several polymorphisms in the TNF gene cluster on chromosome 6p21 have been associated with TNFalpha production and potential increased risk of asthma. The present paper evaluates the relation between two single nucleotide polymorphisms (SNPs) in...
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