Article
Endothelin 1-mediated regulation of pharyngeal bone development in zebrafish.
Development (Cambridge, England) - 1 Apr 2003
Kimmel Charles B, Ullmann Bonnie, Walker Macie, Miller Craig T, Crump Justin G
Abstract excerpt
Endothelin 1 (Edn1), a secreted peptide expressed ventrally in the primordia of the zebrafish pharyngeal arches, is required for correct patterning of pharyngeal cartilage development. We have studied mutants and morpholino-injected larvae to examine the role of the Edn1 signal in patterning anterior pharyngeal arch bone development during the first week after fertilization. We observe a remarkable variety of...
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