Article
Spontaneous mutations in the Helicobacter pylori rpsL gene.
Mutation research - 3 Mar 2003
Torii Naotaka, Nozaki Tadashige, Masutani Mitsuko, Nakagama Hitoshi, Sugiyama Toshiro, Saito Daizo, Asaka Masahiro, Sugimura Takashi, Miki Kazumasa
Abstract excerpt
Several studies have revealed that the Helicobacter pylori genome differs markedly from strain to strain, perhaps as a result of mutations arising during persistent infection and/or related to the observed variation in virulence. The development of a detection system for mutations in H. pylori genes might therefore help us to develop a better understanding of its mutability, and in this way help us to develop...
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