Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bombesin receptor subtype-3 modulates plasma insulin concentration.

Peptides - 1 Jan 2003

Matsumoto Kouji, Yamada Kazuyuki, Wada Etsuko, Hasegawa Takanori, Usui Yoshihiro, Wada Keiji

Abstract excerpt

Mice lacking a functional bombesin receptor subtype-3 (BRS-3) develop mild obesity. However, the origin of obesity in BRS-3 knockout (KO) mice remains unclear. We used a strain-crossing strategy to investigate the physiological role of the BRS-3 pathway. We crossed female heterozygous BRS-3 KO mice (X-/X) and male KK-Ay mice (Ay/+) to obtain BRS-3 KO/KK-Ay hybrid animals. In X-/Y:Ay/+ mice, plasma insulin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Feeding Behavior
Share to Drinking Behavior
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose Tolerance Test

Share to Insulin

Source

Identifiers

PMID: 12576088
DOI: 10.1016/s0196-9781(02)00279-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bombesin receptor subtype-3 modulates plasma insulin concentration.PMID 12576088Read ↗

Mutation in bombesin receptor subtype-3 gene is not a major cause of obesity in the Japanese.Semantic proximity Read ↗

Prostaglandin EP3 Receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistanceSemantic proximity Read ↗

Impact of genetic background and ablation of insulin receptor substrate (IRS)-3 on IRS-2 knock-out mice.Semantic proximity Read ↗

A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo.Semantic proximity Read ↗

Metabolic roles of the M3 muscarinic acetylcholine receptor studied with M3 receptor mutant mice: a review.Semantic proximity Read ↗

Kinin B1 receptor in adipocytes regulates glucose tolerance and predisposition to obesity.Semantic proximity Read ↗

Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1.Semantic proximity Read ↗

Pancreatic Brsk2 amplifies parasympathetic signals to promote type 2 diabetesSemantic proximity Read ↗

Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors.Semantic proximity Read ↗

Targeted disruption of the beta 3-adrenergic receptor gene.Semantic proximity Read ↗

Prostaglandin E2 receptor EP3 regulates both adipogenesis and lipolysis in mouse white adipose tissue.Semantic proximity Read ↗

Reduced proliferation and a high apoptotic frequency of pancreatic beta cells contribute to genetically-determined diabetes susceptibility of db/db BKS mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.