Article
Prostaglandin E2 receptor EP3 regulates both adipogenesis and lipolysis in mouse white adipose tissue.
Journal of molecular cell biology - 1 Dec 2016
Xu Hu, Fu Jia-Lin, Miao Yi-Fei, Wang Chun-Jiong, Han Qi-Fei, Li Sha, Huang Shi-Zheng, Du Sheng-Nan, Qiu Yu-Xiang, Yang Ji-Chun, Gustafsson Jan-Åke, Breyer Richard M, Zheng Feng, Wang Nan-Ping, Zhang Xiao-Yan, Guan You-Fei
Abstract excerpt
Among the four prostaglandin E2 receptors, EP3 receptor is the one most abundantly expressed in white adipose tissue (WAT). The mouse EP3 gene gives rise to three isoforms, namely EP3α, EP3β, and EP3γ, which differ only at their C-terminal tails. To date, functions of EP3 receptor and its isoforms in WAT remain incompletely characterized. In this study, we found that the expression of all EP3 isoforms were...
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