Article
Identification of IgG subclasses and C-reactive protein in lupus nephritis: the relationship between the composition of immune deposits and FCgamma receptor type IIA alleles.
Arthritis and rheumatism - 1 Feb 2003
Zuniga Ricardo, Markowitz Glen S, Arkachaisri Thaschawee, Imperatore Edward A, D'Agati Vivette D, Salmon Jane E
Abstract excerpt
OBJECTIVE: To characterize the subclass composition of IgG deposited in lupus glomeruli, to examine its relationship to allelic polymorphisms of IgG receptors (Fcgamma receptors [FcgammaR]), and to determine whether C-reactive protein (CRP), a ligand for FcgammaRIIa, is present in these immune deposits. METHODS: Renal biopsy samples from 80 patients with lupus nephritis were examined by light microscopy and...
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