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Article

FCGR2B and FCRLB gene polymorphisms associated with IgA nephropathy.

PloS one - 1 Jan 2013

Zhou Xu-jie, Cheng Fa-juan, Qi Yuan-yuan, Zhao Yan-feng, Hou Ping, Zhu Li, Lv Ji-cheng, Zhang Hong

Abstract excerpt

BACKGROUND: IgA nephropathy (IgAN) is a complex syndrome characterized by deposition of IgA and IgA containing immune complexes (ICs) composed of IgG and complement C3 proteins in the mesangial area of glomeruli. The low-affinity receptors for the Fc region of IgG (FcγRs) are involved in autoantibody/immune complex-induced organ injury as well as ICs clearance. The aim of the study was to associate multiple...

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Source

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Identifiers

PMID: 23593433
DOI: 10.1371/journal.pone.0061208
PMCID: PMC3625155

Genes

FCRLB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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