Article
Skewed distribution of IgG Fc receptor IIa (CD32) polymorphism is associated with renal disease in systemic lupus erythematosus patients.
Arthritis and rheumatism - 1 Dec 1995
Duits A J, Bootsma H, Derksen R H, Spronk P E, Kater L, Kallenberg C G, Capel P J, Westerdaal N A, Spierenburg G T, Gmelig-Meyling F H
Abstract excerpt
OBJECTIVE: Fc gamma receptors of class IIa (Fc gamma RIIa) occur in 2 allelic forms, with either a low (IIa-R131) or a high (IIa-H131) affinity for complexed IgG2 and IgG3. This polymorphism might have implications for the handling of immune complexes. Therefore, we determined the distribution of...
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