Article
Association between SLE nephritis and polymorphic variants of the CRP and FcgammaRIIIa genes.
Rheumatology (Oxford, England) - 1 Sept 2007
Jönsen A, Gunnarsson I, Gullstrand B, Svenungsson E, Bengtsson A A, Nived O, Lundberg I E, Truedsson L, Sturfelt G
Abstract excerpt
OBJECTIVES: To study the relationship between clinical manifestations in systemic lupus erythematosus (SLE) with polymorphisms in suggested susceptibility genes encoding FcgammaRIIa, FcgammaRIIIa, FcgammaRIIIb, CRP and IL-1Ra. METHODS: Genetic polymorphisms were analysed in 323 unrelated SLE patients and 200 healthy blood donors. The genotype frequencies were compared between clinical subsets of SLE patients, as...
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