Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathway

4 Jan 2021

Abstract excerpt

Cell division cycle-associated 5 (CDCA5) can regulate cell cycle-related proteins to promote the proliferation of cancer cells. The purpose of the present study was to investigate the expression level of CDCA5 in prostate cancer (PCa) and its effect on PCa progression. The signalling pathway by which CDCA5 functions through was also attempted to elucidate. Clinical specimens of PCa patients were collected from...

Topics

Join the communities discussing this publication.

FOXO transcription factor regulation
Hippo pathway signaling and YAP/TAZ
Prostate Cancer Treatment and Research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33650660
DOI: 10.3892/or.2021.7920

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathwayPMID 33650660Read ↗

Overexpression of CDCA8 Predicts Poor Prognosis and Promotes Tumor Cell Growth in Prostate CancerSemantic proximity Read ↗

Bioinformatics analysis of the clinical relevance of CDCA gene family in prostate cancerSemantic proximity Read ↗

Comprehensive Analysis of Cell Cycle-Related Genes in Patients With Prostate CancerSemantic proximity Read ↗

CDCA5 is a potent therapeutic target of clear cell renal cell carcinomaSemantic proximity Read ↗

Knockdown of spindle pole body component 25 homolog inhibits cell proliferation and cycle progression in prostate cancerSemantic proximity Read ↗

Silencing oncogene cell division cycle associated 5 induces apoptosis and G1 phase arrest of non‐small cell lung cancer cells via p53‐p21 signaling pathwaySemantic proximity Read ↗

Loss of cell division cycle‑associated 5 promotes cell apoptosis by activating DNA damage response in clear cell renal cell carcinomaSemantic proximity Read ↗

Mechanistic and Clinical Evidence Supports a Key Role for Cell Division Cycle Associated 5 (CDCA5) as an Independent Predictor of Outcome in Invasive Breast CancerSemantic proximity Read ↗

Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathwaySemantic proximity Read ↗

Upregulation of CDCA5 promotes gastric cancer malignant progression via influencing cyclin E1Semantic proximity Read ↗

Cell division cycle 20 (CDC20) drives prostate cancer progression via stabilization of β-catenin in cancer stem-like cellsSemantic proximity Read ↗

Loss of CDCA5 Promotes Cell Apoptosis by Activating the DNA Damage Response in Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.