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Article

Additional, physically ordered markers increase linkage signal for bipolar disorder on chromosome 18q22.

Biological psychiatry - 1 Feb 2003

Schulze Thomas G, Chen Yu-Sheng, Badner Judith A, McInnis Melvin G, DePaulo J Raymond, McMahon Francis J

Abstract excerpt

BACKGROUND: We recently reported evidence of linkage of bipolar disorder to chromosome 18q, with a paternal logarithm of odds (LOD) score of 4.67 (p =.004) in a clinically defined subset of families. Like other linkage studies, we had to rely on imprecise genetic maps to establish the marker order. Here, we test for linkage in the same sample with a denser set of markers, now physically ordered according to the...

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Identifiers

PMID: 12559657
DOI: 10.1016/s0006-3223(02)01492-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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