Article
Linkage of bipolar affective disorder to chromosome 18 markers in a new pedigree series.
American journal of human genetics - 1 Dec 1997
McMahon F J, Hopkins P J, Xu J, McInnis M G, Shaw S, Cardon L, Simpson S G, MacKinnon D F, Stine O C, Sherrington R, Meyers D A, DePaulo J R
Abstract excerpt
Several groups have reported evidence suggesting linkage of bipolar affective disorder (BPAD) to chromosome 18. We have reported data from 28 pedigrees that showed linkage to marker loci on 18p and to loci 40 cM distant on 18q. Most of the linkage evidence derived from families with affected phen...
Topics
- Baltimore
- Bipolar Disorder
- Chromosomes, Human, Pair 18
- Disease Susceptibility
- Genetic Linkage
- Genotype
- Humans
- Iowa
- Pedigree
- Phenotype
- Single-Blind Method