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Article

Influence of common XPD and XRCC1 variant alleles on p53 mutations in lung tumors.

Environmental and molecular mutagenesis - 1 Jan 2003

Hou Sai-Mei, Ryk Charlotta, Kannio Annamaria, Angelini Sabrina, Fält Susann, Nyberg Fredrik, Husgafvel-Pursiainen Kirsti

Abstract excerpt

The DNA repair proteins XPD and XRCC1 are involved in the nucleotide and base excision repair of DNA lesions induced by many tobacco and environmental carcinogens. Common variant alleles at the XPD (312Asn, 751Gln) and XRCC1 (399Gln) loci have been identified and associated with increased risk for lung cancer. We therefore investigated a possible effect of these variant alleles on the frequency and spectrum of...

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Identifiers

PMID: 12552590
DOI: 10.1002/em.10128

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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