Article
Polymorphisms in XPD and TP53 and mutation in human lung cancer.
Carcinogenesis - 1 Mar 2005
Mechanic Leah E, Marrogi Aizen J, Welsh Judith A, Bowman Elise D, Khan Mohammed A, Enewold Lindsey, Zheng Yun-Ling, Chanock Stephen, Shields Peter G, Harris Curtis C
Abstract excerpt
The pattern of somatic mutations in TP53 is distinct for particular cancers and carcinogenic exposures, providing clues to disease etiology, e.g. G:C-->T:A mutations in TP53 are more frequently observed in smoking-associated lung cancers. In order to investigate possible causes and mechanisms of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
