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Article

The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer risk.

Carcinogenesis - 1 Apr 2002

Hou Sai-Mei, Fält Susann, Angelini Sabrina, Yang Ke, Nyberg Fredrik, Lambert Bo, Hemminki Kari

Abstract excerpt

The DNA repair protein xeroderma pigmentosum complementation group D (XPD) is involved in the nucleotide excision repair of DNA lesions induced by many tobacco and environmental carcinogens. In order to study the functional impact of the common polymorphisms in XPD exon 10 (G > A, Asp312Asn) and exon 23 (A > C, Lys751Gln), we have genotyped 185 Swedish lung cancer cases (97 smokers and 88 never-smokers) and 162...

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Identifiers

PMID: 11960912
DOI: 10.1093/carcin/23.4.599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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