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Article

Polymorphisms in DNA repair genes XPD and XRCC1 and p53 mutations in lung carcinomas of never-smokers.

Molecular carcinogenesis - 1 Nov 2006

Gao Wei-Min, Romkes Marjorie, Siegfried Jill M, Luketich James D, Keohavong Phouthone

Abstract excerpt

The etiology of lung cancer in population with little or no tobacco exposure is not well understood. Individual genetic susceptibility factors have been suggested to contribute to lung cancer risk in this population. Mutations in the p53 tumor suppressor gene are implicated in the development of lung cancer as they are frequently found in lung tumors from both smokers and never-smokers. In order to determine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16865671
DOI: 10.1002/mc.20208

Genes

XRCC1

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