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Article

Prognostic importance of DNA repair gene polymorphisms of XRCC1 Arg399Gln and XPD Lys751Gln in lung cancer patients from India.

Journal of cancer research and clinical oncology - 1 Jun 2008

Sreeja Leelakumari, Syamala Volga S, Syamala Vani, Hariharan Sreedharan, Raveendran Praveenkumar B, Vijayalekshmi R V, Madhavan Jayaprakash, Ankathil Ravindran

Abstract excerpt

PURPOSE: Inter individual variation in lung cancer susceptibility may be modulated in part through genetic polymorphisms in the DNA repair genes, especially the genes involved in the Base Excision Repair (BER) and nucleotide excision repair (NER) pathway. Two of the genetic polymorphisms, XRCC1Arg399Gln and XPD Lys751Gln have been extensively studied in the association with lung cancer risk, although published...

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Identifiers

PMID: 17952468
DOI: 10.1007/s00432-007-0328-4

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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