Article
Chromosome 8 genetic analysis and phenotypic characterization of 21 ovarian cancer cell lines.
Cancer genetics and cytogenetics - 1 Dec 2002
Arnold Jeremy M, Woollatt Erica, Chenevix-Trench Georgia
Abstract excerpt
The short arm of chromosome 8 undergoes frequent loss of heterozygosity (LOH) in ovarian adenocarcinomas. Fine mapping has identified several distinct critical regions within 8p which undergo rates of LOH of 50% or greater, suggesting that there may be more than one tumor suppressor gene located on this chromosome arm. In an effort to refine the location of these putative tumor suppressor genes by...
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