Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complex CGH alterations on chromosome arm 8p at candidate tumor suppressor gene loci in breast cancer cell lines.

Cancer genetics and cytogenetics - 15 Jul 2005

Venter Deon J, Ramus Susan J, Hammet Fleur M A, de Silva Melanie, Hutchins Anne-Marie, Petrovic Vida, Price Gareth, Armes Jane E

Abstract excerpt

Loss of genetic material from chromosome arm 8p occurs frequently in human breast carcinomas, consistent with this region of the genome harboring one or more tumor suppressor genes (TSGs). We used the complementary techniques of microsatellite-based LOH, high-density FISH, and conventional CGH on 6 breast cancer cell lines (MCF7, SKBR3, T47D, MDA MB453, BT549, and BT474) to investigate the molecular cytogenetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 8

Share to Genes, Tumor Suppressor

Share to In Situ Hybridization, Fluorescence

Share to Loss of Heterozygosity

Share to Microsatellite Repeats

Share to Nucleic Acid Hybridization

Source

Identifiers

PMID: 15993269
DOI: 10.1016/j.cancergencyto.2004.12.007

Genes

DLC1
DUSP4
PCM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complex CGH alterations on chromosome arm 8p at candidate tumor suppressor gene loci in breast cancer cell lines.PMID 15993269Read ↗

Chromosome 8 genetic analysis and phenotypic characterization of 21 ovarian cancer cell lines.Semantic proximity Read ↗

Molecular cytogenetic analysis of 11 new breast cancer cell linesSemantic proximity Read ↗

Loss of heterozygosity from the short arm of chromosome 8 is an early event in breast cancersSemantic proximity Read ↗

Chromosomal Breakpoints in Primary Colon Cancer Cluster at Sites of Structural Variants in the GenomeSemantic proximity Read ↗

Identification of three distinct regions of allelic deletions on the short arm of chromosome 8 in hepatocellular carcinoma.Semantic proximity Read ↗

Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival.Semantic proximity Read ↗

Genetic losses in breast cancer: toward an integrated molecular cytogenetic map.Semantic proximity Read ↗

Allelotype of 28 human breast cancer cell lines and xenografts.Semantic proximity Read ↗

Genetic background of different cancer cell lines influences the gene set involved in chromosome 8 mediated breast tumor suppression.Semantic proximity Read ↗

Comprehensive analysis of copy number and allele status identifies multiple chromosome defects underlying follicular lymphoma pathogenesis.Semantic proximity Read ↗

Gain of a region on 7p22.3, containing <i>MAD1L1</i>, is the most frequent event in small‐cell lung cancer cell linesSemantic proximity Read ↗

Loss of heterozygosity from the short arm of chromosome 8 is associated with invasive behavior in breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.