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Article

Analysis of the candidate 8p21 tumour suppressor, BNIP3L, in breast and ovarian cancer.

British journal of cancer - 27 Jan 2003

Lai J, Flanagan J, Phillips W A, Chenevix-Trench G, Arnold J

Abstract excerpt

Loss of heterozygosity (LOH) on the short arm of chromosome 8, at 8p12-p23, is one of the most frequent genetic events in both breast and ovarian cancer, suggesting the location of a shared tumour suppressor gene. Microcell-mediated chromosome transfer of chromosome 8 suppresses tumorigenicity and growth of colorectal and prostate cancer cell lines, further supporting the presence of a tumour suppressor gene on...

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Share to Carcinoma, Ductal, Breast
Share to Chromosomes, Human, Pair 8

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12610513
DOI: 10.1038/sj.bjc.6600674
PMCID: PMC2377059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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