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Article

Multipoint linkage disequilibrium mapping for complex diseases.

Genetic epidemiology - 1 Dec 2003

Liang Kung-Yee, Hsu Fang-Chi, Beaty Terri H

Abstract excerpt

Linkage disequilibrium (LD) or association studies using case-parent trios have become a common approach to locate unobserved susceptibility genes underlying complex diseases. With the availability of ever more dense marker maps, how to utilize the information carried by multiple markers simultaneously remains challenging. Recently, Liang et al. ([2001a] Am. J. Hum. Genet. 68: 937-950) proposed a multipoint LD...

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PMID: 14639698
DOI: 10.1002/gepi.10271

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