Article
Genetic control of Bordetella pertussis infection: identification of susceptibility loci using recombinant congenic strains of mice.
Infection and immunity - 1 Feb 2005
Banus H A, van Kranen H J, Mooi F R, Hoebee B, Nagelkerke N J, Demant P, Kimman T G
Abstract excerpt
Susceptibility to and severity of Bordetella pertussis infection in infants and children vary widely. The spectrum of clinical symptoms ranges from subclinical infection to mild disease, severe whooping cough, and death. The aims of this study were to examine genetic susceptibilities of mice to B. pertussis and to identify genetic loci in the mouse genome that are involved in susceptibility to B. pertussis...
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