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Article

Mouse genetic model for clinical and immunological heterogeneity of leishmaniasis.

Immunogenetics - 1 Jun 2002

Lipoldová Marie, Svobodová Milena, Havelková Helena, Krulová Magdaléna, Badalová Jana, Nohýnková Eva, Hart Augustinus A M, Schlegel David, Volf Petr, Demant Peter

Abstract excerpt

Systematic assessment of the role of host genes in clinico-pathological and immunological manifestations of Leishmania major-induced disease in mice was performed using 20 recombinant congenic (RC) strains. As the RC strains are homozygous and each carries a different, random set of 12.5% genes from the resistant strain, STS/A, and 87.5% genes from the susceptible strain, BALB/cHeA, they allowed us to study the...

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PMID: 12073146
DOI: 10.1007/s00251-002-0439-7

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STS

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Source receipt: pubmed, retrieved 7 Sept 2026.

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