Article
Relation of risk of systemic lupus erythematosus to west African admixture in a Caribbean population.
Human genetics - 1 Mar 2003
Molokhia M, Hoggart C, Patrick A L, Shriver M, Parra E, Ye J, Silman A J, McKeigue P M
Abstract excerpt
Risk of systemic lupus erythematosus (SLE) is higher in people of west African descent than in Europeans. The objective of this study was to distinguish between genetic and environmental explanations for this ethnic difference by examining the relationship of disease risk to individual admixture (defined as the proportion of the genome that is of west African ancestry); 124 cases of SLE and 219 matched controls...
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