Article
[Correlation of p16 mutation and biological behavior in Chinese laryngeal cancer].
Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology - 1 Jun 2001
Huang H, Cui Y, Tang D, Tao Y, Liu Q
Abstract excerpt
OBJECTIVE: To investigate the correlation between p16 gene mutation and laryngeal cancer biological behavior as well as its prognosis in laryngeal cancer. METHOD: 24 specimens of primary laryngeal cancer and 10 speciments with benign lesion in larynx were examined for mutations in exon2 of p16 by using PCR-SSCP silver stainning technique. RESULT: Mutations frequency of laryngeal cancer was 62.5% (15/24). Nothing...
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