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[The study of p16 gene mutation and methylation in laryngeal squamous cell carcinoma].

Zhonghua er bi yan hou ke za zhi - 1 Aug 2000

Bai S, Gao H, Liang H, Fei S, Zhang X, Sun K

Abstract excerpt

OBJECTIVE: To investigate the development and mechanism of the p16 gene inactivation in laryngeal squamous cell carcinoma (LSCC). METHODS: With PCR-based methylation assay and PCR-SSCP, first and second exon mutation in p16 gene and methylation of endogenase in promoter in 32 cases of LSCC and paracancer tissue were studied. RESULTS: No mutation were found in first and second exon in the samples; methylation of...

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PMID: 12768709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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