Article
[Study of RB gene in carcinoma of larynx].
Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology - 1 Feb 2003
Wang Binquan, Chen Yanqiu, Wen Shuxin, Wang Jianming, Huangpu Hui, Li Yujun
Abstract excerpt
OBJECTIVE: To probe the mutations of RB gene in laryngeal carcinoma, and the relation between it and the clinical phase. METHOD: The mutations were detected by PCR-SSCP (polymerase chain reaction-single strand conformation polymorphism). RESULT: In laryngeal carcinoma, the mutations were identified in 14(15.5%) of 90 samples, of which 2 were large deletion, 12 were abnormal in electrophoresis of SSCP. The...
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